
产品货号:
Z15206
中文名称:
FGFR2抗体
英文名称:
Anti-FGFR2 Antibody (N-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FGFR2 Antibody (N-term) |
指标别名 | BEK;BFR 1;CD332;CEK3;CFD1;ECT1;FGFR 2;FGFR2;JWS;K SAM;KGFR;KSAM;TK14;TK25 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | IHC,WB,FCM,IF |
基因名称 | FGFR2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This FGFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human FGFR2. |
计算分子量 | 92kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | FGFR2 is a member of the fibroblast growth factor receptor family,where amino acid sequence is highly conserved between members and throughout evolution.FGFR family members differ from one another in their ligand affinities and tissue distribution.A full-length representative protein consists of an extracellular region,composed of three immunoglobulin-like domains,a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblast growth factors,setting in motion a cascade of downstream signals,ultimately influencing mitogenesis and differentiation.This particular family member is a high-affinity receptor for acidic,basic and/or keratinocyte growth factor,depending on the isoform.Mutations in the gene are associated with many craniosynostotic syndromes and bone malformations.The genomic organization of the gene encompasses 20 exons.Alternative splicing in multiple exons,including those encoding the Ig-like domains,the transmembrane region and the carboxyl terminus,results in varied isoforms which differ in structure and specificity.Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF. |
Uniprot ID | P21802 |
相关搜索:FGFR2抗体,FGFR2(N-term)多抗,Anti-FGFR2 Antibody (N-term)